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The FAK–Arp2/3 interaction promotes leading edge advance and haptosensing by coupling nascent adhesions to lamellipodia actin

Cell migration is initiated in response to biochemical or physical cues in the environment that promote actin-mediated lamellipodial protrusion followed by the formation of nascent integrin adhesions (NAs) within the protrusion to drive leading edge advance. Although FAK is known to be required for...

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Bibliografiset tiedot
Julkaisussa:Mol Biol Cell
Päätekijät: Swaminathan, Vinay, Fischer, R. S., Waterman, Clare M.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: The American Society for Cell Biology 2016
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC4814217/
https://ncbi.nlm.nih.gov/pubmed/26842895
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E15-08-0590
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