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Two Functionally Distinct Sources of Actin Monomers Supply the Leading Edge of Lamellipodia

Lamellipodia, the sheet-like protrusions of motile cells, consist of networks of actin filaments (F-actin) regulated by the ordered assembly from and disassembly into actin monomers (G-actin). Traditionally, G-actin is thought to exist as a homogeneous pool. Here, we show that there are two function...

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Dettagli Bibliografici
Pubblicato in:Cell Rep
Autori principali: Vitriol, Eric A., McMillen, Laura M., Kapustina, Maryna, Gomez, Shawn M., Vavylonis, Dimitrios, Zheng, James Q.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2015
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4418508/
https://ncbi.nlm.nih.gov/pubmed/25865895
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2015.03.033
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