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Human Cells Require Non-stop Ribosome Rescue Activity in Mitochondria
Bacteria use trans-translation and the alternative rescue factors ArfA (P36675) and ArfB (Q9A8Y3) to hydrolyze peptidyl-tRNA on ribosomes that stall near the 3' end of an mRNA during protein synthesis. The eukaryotic protein ICT1 (Q14197) is homologous to ArfB. In vitro ribosome rescue assays o...
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| 出版年: | PLoS Genet |
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| 主要な著者: | , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
Public Library of Science
2016
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4814080/ https://ncbi.nlm.nih.gov/pubmed/27029019 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1005964 |
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