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Ribosome Rescue and Translation Termination at Non-Standard Stop Codons by ICT1 in Mammalian Mitochondria

Release factors (RFs) govern the termination phase of protein synthesis. Human mitochondria harbor four different members of the class 1 RF family: RF1Lmt/mtRF1a, RF1mt, C12orf65 and ICT1. The homolog of the essential ICT1 factor is widely distributed in bacteria and organelles and has the peculiar...

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Autors principals: Akabane, Shiori, Ueda, Takuya, Nierhaus, Knud H., Takeuchi, Nono
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2014
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4169044/
https://ncbi.nlm.nih.gov/pubmed/25233460
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1004616
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