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Development of β-amino-carbonyl compounds as androgen receptor antagonists

AIM: Androgen receptor (AR) antagonists have proven to be useful in the early control of prostate cancer. The aim of this study was to identify and characterize a novel β-amino-carbonyl-based androgen receptor antagonist. METHODS: Different isomers of the β-amino-carbonyl compounds were obtained by...

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Detalhes bibliográficos
Publicado no:Acta Pharmacol Sin
Main Authors: Zhang, Zhi-yun, Zhu, Yan-hui, Zhou, Cai-hong, Liu, Qing, Lu, Hui-li, Ge, Yun-jun, Wang, Ming-wei
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4814037/
https://ncbi.nlm.nih.gov/pubmed/24786235
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/aps.2013.201
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