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Intranasal co-delivery of IL-6 gene enhances the immunogenicity of anti-caries DNA vaccine
AIM: To investigate the effects of co-delivering IL-6 expressing plasmid pCI-IL-6 on the immunogenicity of the anti-caries DNA vaccine pCIA-P, which encodes the surface protein antigen PAc of Streptococcus mutans. METHODS: Plasmid pCI-IL-6 was constructed by inserting the murine IL-6 gene into the p...
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| Publicado no: | Acta Pharmacol Sin |
|---|---|
| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4814028/ https://ncbi.nlm.nih.gov/pubmed/24705100 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/aps.2013.184 |
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