CCL17 combined with CCL19 as a nasal adjuvant enhances the immunogenicity of an anti-caries DNA vaccine in rodents

AIM: CCL19 and its receptor CCR7 are essential molecules for facilitating the trafficking of mature dendritic cells (DCs) and helping to establish a microenvironment in lymphoid tissues to initiate primary immune responses, whereas CCL17 is required in the CCR7-CCL19-dependent migration of DCs. In t...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Acta Pharmacol Sin
Prif Awduron: Yan, Yan-hong, Yu, Fei, Zeng, Chang, Cao, Li-hua, Zhang, Zhou, Xu, Qing-an
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Nature Publishing Group 2016
Pynciau:
Original Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC5022104/
https://ncbi.nlm.nih.gov/pubmed/27546005
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/aps.2016.73
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