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Docetaxel-induced polyploidization may underlie chemoresistance and disease relapse

Although docetaxel significantly improves survival in a variety of malignancies, its clinical utility is severely restricted by acquired chemoresistance and disease relapse. To uncover the mechanisms underlying these all too common occurrences, an abundance of research has focused on mutations and g...

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Detalles Bibliográficos
Publicado en:Cancer Lett
Main Authors: Ogden, Angela, Rida, Padmashree C.G., Knudsen, Beatrice, Kucuk, Omer, Aneja, Ritu
Formato: Artigo
Idioma:Inglês
Publicado: 2015
Assuntos:
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4813805/
https://ncbi.nlm.nih.gov/pubmed/26185000
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.canlet.2015.06.025
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