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Docetaxel-induced polyploidization may underlie chemoresistance and disease relapse
Although docetaxel significantly improves survival in a variety of malignancies, its clinical utility is severely restricted by acquired chemoresistance and disease relapse. To uncover the mechanisms underlying these all too common occurrences, an abundance of research has focused on mutations and g...
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| Veröffentlicht in: | Cancer Lett |
|---|---|
| Hauptverfasser: | , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2015
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4813805/ https://ncbi.nlm.nih.gov/pubmed/26185000 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.canlet.2015.06.025 |
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