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Opportunistic DNA Recombination With Epstein-Barr Virus at Sites of Control Region Rearrangements Mediating JC Virus Neurovirulence

We document a unique DNA recombination between polyomavirus JC (JC virus [JCV]) and Epstein-Barr virus (EBV) at sequences of JCV found infecting the brain. Archetype JCV is present in bone marrow and uroepithelial cells of most adults. During immunosuppression, JCV can infect the brain, causing a de...

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Détails bibliographiques
Publié dans:J Infect Dis
Auteurs principaux: Wortman, Margaret J., Lundberg, Patric S., Dagdanova, Ayuna V., Venkataraman, Pranav, Daniel, Dianne C., Johnson, Edward M.
Format: Artigo
Langue:Inglês
Publié: Oxford University Press 2016
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Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4813741/
https://ncbi.nlm.nih.gov/pubmed/26690342
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/infdis/jiv755
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