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Polyomavirus JC in the Context of Immunosuppression: A Series of Adaptive, DNA Replication-Driven Recombination Events in the Development of Progressive Multifocal Leukoencephalopathy

Polyomavirus JC (JCV) is the etiological agent of progressive multifocal leukoencephalopathy (PML), a demyelinating infection of oligodendrocytes in the brain. PML, a frequently fatal opportunistic infection in AIDS, has also emerged as a consequence of treatment with several new immunosuppressive t...

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Detalhes bibliográficos
Main Authors: Johnson, Edward M., Wortman, Margaret J., Dagdanova, Ayuna V., Lundberg, Patric S., Daniel, Dianne C.
Formato: Artigo
Idioma:Inglês
Publicado em: Hindawi Publishing Corporation 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3649189/
https://ncbi.nlm.nih.gov/pubmed/23690820
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2013/197807
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