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Quantitative Mass Spectrometry Reveals that Intact Histone H1 Phosphorylations are Variant Specific and Exhibit Single Molecule Hierarchical Dependence

Breast cancer was the second leading cause of cancer related mortality for females in 2014. Recent studies suggest histone H1 phosphorylation may be useful as a clinical biomarker of breast and other cancers because of its ability to recognize proliferative cell populations. Although monitoring a si...

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Détails bibliographiques
Publié dans:Mol Cell Proteomics
Auteurs principaux: Chen, Yu, Hoover, Michael E., Dang, Xibei, Shomo, Alan A., Guan, Xiaoyan, Marshall, Alan G., Freitas, Michael A., Young, Nicolas L.
Format: Artigo
Langue:Inglês
Publié: The American Society for Biochemistry and Molecular Biology 2016
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Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4813703/
https://ncbi.nlm.nih.gov/pubmed/26209608
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/mcp.M114.046441
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