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Discovery of Histone Modification Crosstalk Networks by Stable Isotope Labeling of Amino Acids in Cell Culture Mass Spectrometry (SILAC MS)

In this paper we describe an approach that combines stable isotope labeling of amino acids in cells culture, high mass accuracy liquid chromatography tandem mass spectrometry and a novel data analysis approach to accurately determine relative peptide post-translational modification levels. This pape...

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Auteurs principaux: Guan, Xiaoyan, Rastogi, Neha, Parthun, Mark R., Freitas, Michael A.
Format: Artigo
Langue:Inglês
Publié: The American Society for Biochemistry and Molecular Biology 2013
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3734568/
https://ncbi.nlm.nih.gov/pubmed/23592332
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/mcp.M112.026716
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