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Discovery of Histone Modification Crosstalk Networks by Stable Isotope Labeling of Amino Acids in Cell Culture Mass Spectrometry (SILAC MS)

In this paper we describe an approach that combines stable isotope labeling of amino acids in cells culture, high mass accuracy liquid chromatography tandem mass spectrometry and a novel data analysis approach to accurately determine relative peptide post-translational modification levels. This pape...

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Detalhes bibliográficos
Main Authors: Guan, Xiaoyan, Rastogi, Neha, Parthun, Mark R., Freitas, Michael A.
Formato: Artigo
Idioma:Inglês
Publicado em: The American Society for Biochemistry and Molecular Biology 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3734568/
https://ncbi.nlm.nih.gov/pubmed/23592332
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/mcp.M112.026716
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