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Discovery of Histone Modification Crosstalk Networks by Stable Isotope Labeling of Amino Acids in Cell Culture Mass Spectrometry (SILAC MS)

In this paper we describe an approach that combines stable isotope labeling of amino acids in cells culture, high mass accuracy liquid chromatography tandem mass spectrometry and a novel data analysis approach to accurately determine relative peptide post-translational modification levels. This pape...

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Hlavní autoři: Guan, Xiaoyan, Rastogi, Neha, Parthun, Mark R., Freitas, Michael A.
Médium: Artigo
Jazyk:Inglês
Vydáno: The American Society for Biochemistry and Molecular Biology 2013
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3734568/
https://ncbi.nlm.nih.gov/pubmed/23592332
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/mcp.M112.026716
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