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Building and re-building the heart by cardiomyocyte proliferation

The adult human heart does not regenerate significant amounts of lost tissue after injury. Rather than making new, functional muscle, human hearts are prone to scarring and hypertrophy, which can often lead to fatal arrhythmias and heart failure. The most-cited basis of this ineffective cardiac rege...

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Detalhes bibliográficos
Publicado no:Development
Main Authors: Foglia, Matthew J., Poss, Kenneth D.
Formato: Artigo
Idioma:Inglês
Publicado em: The Company of Biologists Ltd 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4813344/
https://ncbi.nlm.nih.gov/pubmed/26932668
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dev.132910
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