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BMP signaling and cellular dynamics during regeneration of airway epithelium from basal progenitors

The pseudostratified epithelium of the lung contains ciliated and secretory luminal cells and basal stem/progenitor cells. To identify signals controlling basal cell behavior we screened factors that alter their self-renewal and differentiation in a clonal organoid (tracheosphere) assay. This reveal...

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Pubblicato in:Development
Autori principali: Tadokoro, Tomomi, Gao, Xia, Hong, Charles C., Hotten, Danielle, Hogan, Brigid L. M.
Natura: Artigo
Lingua:Inglês
Pubblicazione: The Company of Biologists Ltd 2016
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4813333/
https://ncbi.nlm.nih.gov/pubmed/26811382
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dev.126656
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