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A grid-based backbone correction to the ff12SB protein force field for implicit-solvent simulations

Force fields, such as Amber’s ff12SB, can be fairly accurate models of the physical forces in proteins and other biomolecules. When coupled with accurate solvation models, force fields are able to bring insight into the conformational preferences, transitions, pathways and free energies for these bi...

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Detalhes bibliográficos
Publicado no:J Chem Theory Comput
Main Authors: Perez, Alberto, MacCallum, Justin L., Brini, Emiliano, Simmerling, Carlos, Dill, Ken A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4813323/
https://ncbi.nlm.nih.gov/pubmed/26574266
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.jctc.5b00662
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