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Genetic Deletion of Rab27B in Pancreatic Acinar Cells Affects Granules Size and has Inhibitory Effects on Amylase Secretion

Small G protein Rab27B is expressed in various secretory cell types and plays a role in mediating secretion. In pancreatic acinar cells, Rab27B was found to be expressed on the zymogen granule membrane and by overexpression to regulate the secretion of zymogen granules. However, the effect of Rab27B...

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Publicat a:Biochem Biophys Res Commun
Autors principals: Hou, Yanan, Ernst, Stephen A., Lentz, Stephen I., Williams, John A.
Format: Artigo
Idioma:Inglês
Publicat: 2016
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4813283/
https://ncbi.nlm.nih.gov/pubmed/26845357
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbrc.2016.01.180
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