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Genetic Deletion of Rab27B in Pancreatic Acinar Cells Affects Granules Size and has Inhibitory Effects on Amylase Secretion

Small G protein Rab27B is expressed in various secretory cell types and plays a role in mediating secretion. In pancreatic acinar cells, Rab27B was found to be expressed on the zymogen granule membrane and by overexpression to regulate the secretion of zymogen granules. However, the effect of Rab27B...

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Bibliographic Details
Published in:Biochem Biophys Res Commun
Main Authors: Hou, Yanan, Ernst, Stephen A., Lentz, Stephen I., Williams, John A.
Format: Artigo
Language:Inglês
Published: 2016
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4813283/
https://ncbi.nlm.nih.gov/pubmed/26845357
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbrc.2016.01.180
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