First-Generation Antipsychotic Haloperidol Alters the Functionality of the Late Endosomal/Lysosomal Compartment in Vitro

First- and second-generation antipsychotics (FGAs and SGAs, respectively), have the ability to inhibit cholesterol biosynthesis and also to interrupt the intracellular cholesterol trafficking, interfering with low-density lipoprotein (LDL)-derived cholesterol egress from late endosomes/lysosomes. In...

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Detalhes bibliográficos
Publicado no:Int J Mol Sci
Main Authors: Canfrán-Duque, Alberto, Barrio, Luis C., Lerma, Milagros, de la Peña, Gema, Serna, Jorge, Pastor, Oscar, Lasunción, Miguel A., Busto, Rebeca
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2016
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4813259/
https://ncbi.nlm.nih.gov/pubmed/26999125
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms17030404
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