Transcriptome study and identification of potential marker genes related to the stable expression of recombinant proteins in CHO clones

BACKGROUND: Chinese hamster ovary (CHO) cells have become the host of choice for the production of recombinant proteins, due to their capacity for correct protein folding, assembly, and posttranslational modifications. The most widely used system for recombinant proteins is the gene amplification pr...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:BMC Biotechnol
Main Authors: Jamnikar, Uros, Nikolic, Petra, Belic, Ales, Blas, Marjanca, Gaser, Dominik, Francky, Andrej, Laux, Holger, Blejec, Andrej, Baebler, Spela, Gruden, Kristina
Format: Artigo
Jezik:Inglês
Izdano: BioMed Central 2015
Teme:
Research Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4812793/
https://ncbi.nlm.nih.gov/pubmed/26499110
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12896-015-0218-9
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