Transcriptome study and identification of potential marker genes related to the stable expression of recombinant proteins in CHO clones

BACKGROUND: Chinese hamster ovary (CHO) cells have become the host of choice for the production of recombinant proteins, due to their capacity for correct protein folding, assembly, and posttranslational modifications. The most widely used system for recombinant proteins is the gene amplification pr...

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Publicado no:BMC Biotechnol
Main Authors: Jamnikar, Uros, Nikolic, Petra, Belic, Ales, Blas, Marjanca, Gaser, Dominik, Francky, Andrej, Laux, Holger, Blejec, Andrej, Baebler, Spela, Gruden, Kristina
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2015
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4812793/
https://ncbi.nlm.nih.gov/pubmed/26499110
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12896-015-0218-9
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https://ncbi.nlm.nih.gov/pmc/articles/PMC4812793/
https://ncbi.nlm.nih.gov/pubmed/26499110
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12896-015-0218-9