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Topologically associated domains enriched for lineage-specific genes reveal expression-dependent nuclear topologies during myogenesis

The linear distribution of genes across chromosomes and the spatial localization of genes within the nucleus are related to their transcriptional regulation. The mechanistic consequences of linear gene order, and how it may relate to the functional output of genome organization, remain to be fully r...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: Neems, Daniel S., Garza-Gongora, Arturo G., Smith, Erica D., Kosak, Steven T.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4812766/
https://ncbi.nlm.nih.gov/pubmed/26957603
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1521826113
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