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ppGpp negatively impacts ribosome assembly affecting growth and antimicrobial tolerance in Gram-positive bacteria

The stringent response is a survival mechanism used by bacteria to deal with stress. It is coordinated by the nucleotides guanosine tetraphosphate and pentaphosphate [(p)ppGpp], which interact with target proteins to promote bacterial survival. Although this response has been well characterized in p...

Πλήρης περιγραφή

Αποθηκεύτηκε σε:
Λεπτομέρειες βιβλιογραφικής εγγραφής
Τόπος έκδοσης:Proc Natl Acad Sci U S A
Κύριοι συγγραφείς: Corrigan, Rebecca M., Bellows, Lauren E., Wood, Alison, Gründling, Angelika
Μορφή: Artigo
Γλώσσα:Inglês
Έκδοση: National Academy of Sciences 2016
Θέματα:
Διαθέσιμο Online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4812758/
https://ncbi.nlm.nih.gov/pubmed/26951678
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1522179113
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