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How the initiating ribosome copes with ppGpp to translate mRNAs

During host colonization, bacteria use the alarmones (p)ppGpp to reshape their proteome by acting pleiotropically on DNA, RNA, and protein synthesis. Here, we elucidate how the initiating ribosome senses the cellular pool of guanosine nucleotides and regulates the progression towards protein synthes...

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Vydáno v:PLoS Biol
Hlavní autoři: Vinogradova, Daria S., Zegarra, Victor, Maksimova, Elena, Nakamoto, Jose Alberto, Kasatsky, Pavel, Paleskava, Alena, Konevega, Andrey L., Milón, Pohl
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science 2020
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7010297/
https://ncbi.nlm.nih.gov/pubmed/31995552
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pbio.3000593
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