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How the initiating ribosome copes with ppGpp to translate mRNAs

During host colonization, bacteria use the alarmones (p)ppGpp to reshape their proteome by acting pleiotropically on DNA, RNA, and protein synthesis. Here, we elucidate how the initiating ribosome senses the cellular pool of guanosine nucleotides and regulates the progression towards protein synthes...

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Dades bibliogràfiques
Publicat a:PLoS Biol
Autors principals: Vinogradova, Daria S., Zegarra, Victor, Maksimova, Elena, Nakamoto, Jose Alberto, Kasatsky, Pavel, Paleskava, Alena, Konevega, Andrey L., Milón, Pohl
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2020
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7010297/
https://ncbi.nlm.nih.gov/pubmed/31995552
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pbio.3000593
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