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Rapid expansion of the protein disulfide isomerase gene family facilitates the folding of venom peptides

Formation of correct disulfide bonds in the endoplasmic reticulum is a crucial step for folding proteins destined for secretion. Protein disulfide isomerases (PDIs) play a central role in this process. We report a previously unidentified, hypervariable family of PDIs that represents the most diverse...

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Xehetasun bibliografikoak
Argitaratua izan da:Proc Natl Acad Sci U S A
Egile Nagusiak: Safavi-Hemami, Helena, Li, Qing, Jackson, Ronneshia L., Song, Albert S., Boomsma, Wouter, Bandyopadhyay, Pradip K., Gruber, Christian W., Purcell, Anthony W., Yandell, Mark, Olivera, Baldomero M., Ellgaard, Lars
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: National Academy of Sciences 2016
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC4812716/
https://ncbi.nlm.nih.gov/pubmed/26957604
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1525790113
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