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Discovery and characterization of a novel CCND1/MRCK gene fusion in mantle cell lymphoma
The t(11;14) translocation resulting in constitutive cyclin D1 expression is an early event in mantle cell lymphoma (MCL) transformation. Patients with a highly proliferative phenotype produce cyclin D1 transcripts with truncated 3′UTRs that evade miRNA regulation. Here, we report the recurrence of...
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Publicado no: | J Hematol Oncol |
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Main Authors: | , , |
Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
BioMed Central
2016
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4812644/ https://ncbi.nlm.nih.gov/pubmed/27025456 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13045-016-0260-7 |
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