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Pneumococcal Pneumolysin Induces DNA Damage and Cell Cycle Arrest
Streptococcus pneumoniae produces pneumolysin toxin as a key virulence factor against host cells. Pneumolysin is a cholesterol-dependent cytolysin (CDC) toxin that forms lytic pores in host membranes and mediates pneumococcal disease pathogenesis by modulating inflammatory responses. Here, we show t...
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| Publicado no: | Sci Rep |
|---|---|
| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4812240/ https://ncbi.nlm.nih.gov/pubmed/27026501 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep22972 |
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