Mitochondrial gene polymorphisms alter hepatic cellular energy metabolism and aggravate diet-induced non-alcoholic steatohepatitis

OBJECTIVE: Non-alcoholic fatty liver disease (NAFLD) is the most common chronic liver disease and is associated with an enhanced risk for liver and cardiovascular diseases and mortality. NAFLD can progress from simple hepatic steatosis to non-alcoholic steatohepatitis (NASH). However, the mechanisms...

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Detalhes bibliográficos
Publicado no:Mol Metab
Main Authors: Schröder, Torsten, Kucharczyk, David, Bär, Florian, Pagel, René, Derer, Stefanie, Jendrek, Sebastian Torben, Sünderhauf, Annika, Brethack, Ann-Kathrin, Hirose, Misa, Möller, Steffen, Künstner, Axel, Bischof, Julia, Weyers, Imke, Heeren, Jörg, Koczan, Dirk, Schmid, Sebastian Michael, Divanovic, Senad, Giles, Daniel Aaron, Adamski, Jerzy, Fellermann, Klaus, Lehnert, Hendrik, Köhl, Jörg, Ibrahim, Saleh, Sina, Christian
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2016
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Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4812012/
https://ncbi.nlm.nih.gov/pubmed/27069868
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molmet.2016.01.010
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