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Mitochondrial gene polymorphisms alter hepatic cellular energy metabolism and aggravate diet-induced non-alcoholic steatohepatitis

OBJECTIVE: Non-alcoholic fatty liver disease (NAFLD) is the most common chronic liver disease and is associated with an enhanced risk for liver and cardiovascular diseases and mortality. NAFLD can progress from simple hepatic steatosis to non-alcoholic steatohepatitis (NASH). However, the mechanisms...

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書誌詳細
出版年:Mol Metab
主要な著者: Schröder, Torsten, Kucharczyk, David, Bär, Florian, Pagel, René, Derer, Stefanie, Jendrek, Sebastian Torben, Sünderhauf, Annika, Brethack, Ann-Kathrin, Hirose, Misa, Möller, Steffen, Künstner, Axel, Bischof, Julia, Weyers, Imke, Heeren, Jörg, Koczan, Dirk, Schmid, Sebastian Michael, Divanovic, Senad, Giles, Daniel Aaron, Adamski, Jerzy, Fellermann, Klaus, Lehnert, Hendrik, Köhl, Jörg, Ibrahim, Saleh, Sina, Christian
フォーマット: Artigo
言語:Inglês
出版事項: Elsevier 2016
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC4812012/
https://ncbi.nlm.nih.gov/pubmed/27069868
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molmet.2016.01.010
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