Induction of Macrophage Function in Human THP-1 Cells Is Associated with Rewiring of MAPK Signaling and Activation of MAP3K7 (TAK1) Protein Kinase

Macrophages represent the primary human host response to pathogen infection and link the immediate defense to the adaptive immune system. Mature tissue macrophages convert from circulating monocyte precursor cells by terminal differentiation in a process that is not fully understood. Here, we analyz...

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Vydáno v:Front Cell Dev Biol
Hlavní autoři: Richter, Erik, Ventz, Katharina, Harms, Manuela, Mostertz, Jörg, Hochgräfe, Falko
Médium: Artigo
Jazyk:Inglês
Vydáno: Frontiers Media S.A. 2016
Témata:
Cell and Developmental Biology
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4811913/
https://ncbi.nlm.nih.gov/pubmed/27066479
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fcell.2016.00021
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