Biochemical characterization of the tetrahydrobiopterin synthesis pathway in the oleaginous fungus Mortierella alpina

We characterized the de novo biosynthetic pathway of tetrahydrobiopterin (BH(4)) in the lipid-producing fungus Mortierella alpina. The BH(4) cofactor is essential for various cell processes, and is probably present in every cell or tissue of higher organisms. Genes encoding two copies of GTP cyclohy...

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Bibliographic Details
Published in:Microbiology (Reading)
Main Authors: Wang, Hongchao, Yang, Bo, Hao, Guangfei, Feng, Yun, Chen, Haiqin, Feng, Lu, Zhao, Jianxin, Zhang, Hao, Chen, Yong Q., Wang, Lei, Chen, Wei
Format: Artigo
Language:Inglês
Published: Society for General Microbiology 2011
Subjects:
Cell and Molecular Biology of Microbes
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4811656/
https://ncbi.nlm.nih.gov/pubmed/21852350
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1099/mic.0.051847-0
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