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Discrimination of germline V genes at different sequencing lengths and mutational burdens: a new tool for identifying and evaluating the reliability of V gene assignment

Immune repertoires are collections of lymphocytes that express diverse antigen receptor gene rearrangements consisting of Variable (V), (Diversity (D) in the case of heavy chains) and Joining (J) gene segments. Clonally related cells typically share the same germline gene segments and have highly si...

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Detalhes bibliográficos
Publicado no:J Immunol Methods
Main Authors: Zhang, Bochao, Meng, Wenzhao, Luning Prak, Eline T., Hershberg, Uri
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4811607/
https://ncbi.nlm.nih.gov/pubmed/26529062
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jim.2015.10.009
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