Epigenetic regulation of ZEB1-RAB25/ESRP1 axis plays a critical role in phenylbutyrate treatment-resistant breast cancer

Phenylbutyrate (PB) is a histone deacetylase antagonist that also exhibits antitumor activity. In this study, we used 7 breast cancer cell lines to identify biomarker candidates that predict PB sensitivity in breast cancer. Comprehensive gene expression profiles were compared using microarrays, and...

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Bibliographic Details
Published in:Oncotarget
Main Authors: Kikuchi, Mariko, Yamashita, Keishi, Waraya, Mina, Minatani, Naoko, Ushiku, Hideki, Kojo, Ken, Ema, Akira, Kosaka, Yoshimasa, Katoh, Hiroshi, Sengoku, Norihiko, Enomoto, Takumo, Tanino, Hirokazu, Sawanobori, Masakazu, Watanabe, Masahiko
Format: Artigo
Language:Inglês
Published: Impact Journals LLC 2015
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Research Paper
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4811494/
https://ncbi.nlm.nih.gov/pubmed/26646320
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