MicroRNAs Circulate in the Hemolymph of Drosophila and Accumulate Relative to Tissue microRNAs in an Age-Dependent Manner

In mammals, extracellular miRNAs circulate in biofluids as stable entities that are secreted by normal and diseased tissues, and can enter cells and regulate gene expression. Drosophila melanogaster is a proven system for the study of human diseases. They have an open circulatory system in which hem...

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Bibliographic Details
Published in:Genomics Insights
Main Authors: Dhahbi, Joseph M., Atamna, Hani, Li, Rui, Yamakawa, Amy, Guerrero, Noel, Lam, Hanh T., Mote, Patricia, Spindler, Stephen R.
Format: Artigo
Language:Inglês
Published: Libertas Academica 2016
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Original Research
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4811268/
https://ncbi.nlm.nih.gov/pubmed/27042094
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4137/GEI.S38147
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