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Substituting mouse transcription factor Pou4f2 with a sea urchin orthologue restores retinal ganglion cell development
Pou domain transcription factor Pou4f2 is essential for the development of retinal ganglion cells (RGCs) in the vertebrate retina. A distant orthologue of Pou4f2 exists in the genome of the sea urchin (class Echinoidea) Strongylocentrotus purpuratus (SpPou4f1/2), yet the photosensory structure of se...
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| Publicado no: | Proc Biol Sci |
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| Main Authors: | , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
The Royal Society
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4810862/ https://ncbi.nlm.nih.gov/pubmed/26962139 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1098/rspb.2015.2978 |
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