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Mutation in mitochondrial complex I ND6 subunit is associated with defective response to hypoxia in human glioma cells

BACKGROUND: Hypoxia-tolerant human glioma cells reduce oxygen consumption rate in response to oxygen deficit, a defense mechanism that contributes to survival under moderately hypoxic conditions. In contrast, hypoxia-sensitive cells lack this ability. As it has been previously shown that hypoxia-tol...

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Detalhes bibliográficos
Main Authors: DeHaan, Carrie, Habibi-Nazhad, Bahram, Yan, Elizabeth, Salloum, Nicole, Parliament, Matthew, Allalunis-Turner, Joan
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2004
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC481082/
https://ncbi.nlm.nih.gov/pubmed/15248896
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1476-4598-3-19
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