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Vascular endothelial growth factor expression is independent of hypoxia in human malignant glioma spheroids and tumours

We recently showed that severe hypoxia was not universally present adjacent to necrosis in human glioma xenografts and spheroids established from the M059K, M006, M006X, M006XLo and M010b cell lines. Using these glioma models, we wished to test whether oxygen serves as a regulator of cellular VEGF e...

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Autors principals: Parliament, M B, Allalunis-Turner, M J, Franko, A J, Olive, P L, Mandyam, R, Santos, C, Wolokoff, B
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group 2000
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2363312/
https://ncbi.nlm.nih.gov/pubmed/10682677
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1054/bjoc.1999.0975
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