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TGF-β/SMAD Pathway and Its Regulation in Hepatic Fibrosis

Transforming growth factor-beta1 (TGF-β1), a key member in the TGF-β superfamily, plays a critical role in the development of hepatic fibrosis. Its expression is consistently elevated in affected organs, which correlates with increased extracellular matrix deposition. SMAD proteins have been studied...

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Bibliografiske detaljer
Udgivet i:J Histochem Cytochem
Main Authors: Xu, Fengyun, Liu, Changwei, Zhou, Dandan, Zhang, Lei
Format: Artigo
Sprog:Inglês
Udgivet: SAGE Publications 2016
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4810800/
https://ncbi.nlm.nih.gov/pubmed/26747705
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1369/0022155415627681
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