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Infection of a Single Cell Line with Distinct Strains of Human Cytomegalovirus Can Result in Large Variations in Virion Production and Facilitate Efficient Screening of Virus Protein Function

Previously, we reported that the absence of the ataxia telangiectasia mutated (ATM) kinase, a critical DNA damage response (DDR) signaling component for double-strand breaks, caused no change in HCMV Towne virion production. Later, others reported decreased AD169 viral titers in the absence of ATM....

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Dades bibliogràfiques
Publicat a:J Virol
Autors principals: Zavala, Anamaria G., O'Dowd, John M., Fortunato, Elizabeth A.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology 2016
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4810728/
https://ncbi.nlm.nih.gov/pubmed/26676783
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01762-15
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