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HCMV-Infected Cells Maintain Efficient Nucleotide Excision Repair of the Viral Genome while Abrogating Repair of the Host Genome

Many viruses subvert the host cell's ability to mount and complete various DNA damage responses (DDRs) after infection. HCMV infection of permissive fibroblasts activates host DDRs at the time of viral deposition and during replication, but the DDRs remain uncompleted without arrest or apoptosi...

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Detalhes bibliográficos
Main Authors: O'Dowd, John M., Zavala, Anamaria G., Brown, Celeste J., Mori, Toshio, Fortunato, Elizabeth A.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3510244/
https://ncbi.nlm.nih.gov/pubmed/23209410
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1003038
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