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Identification of Novel Fusion Inhibitors of Influenza A Virus by Chemical Genetics

A previous screening of more than 50,000 compounds led to the identification of a pool of bioactive small molecules with inhibitory effect on the influenza A virus. One of these compounds, now widely known as nucleozin, is a small molecule that targets the influenza A virus nucleoprotein. Here we id...

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Detalhes bibliográficos
Publicado no:J Virol
Main Authors: Lai, Kin Kui, Cheung, Nam Nam, Yang, Fang, Dai, Jun, Liu, Li, Chen, Zhiwei, Sze, Kong Hung, Chen, Honglin, Yuen, Kwok-Yung, Kao, Richard Yi Tsun
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4810722/
https://ncbi.nlm.nih.gov/pubmed/26676787
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.02326-15
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