A Subset of CD4/CD8 Double-Negative T Cells Expresses HIV Proteins in Patients on Antiretroviral Therapy

A major goal in HIV eradication research is characterizing the reservoir cells that harbor HIV in the presence of antiretroviral therapy (ART), which reseed viremia after treatment is stopped. In general, it is assumed that the reservoir consists of CD4(+) T cells that express no viral proteins. How...

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Bibliographische Detailangaben
Veröffentlicht in:J Virol
Hauptverfasser: DeMaster, Laura K., Liu, Xiaohe, VanBelzen, D. Jake, Trinité, Benjamin, Zheng, Lingjie, Agosto, Luis M., Migueles, Stephen A., Connors, Mark, Sambucetti, Lidia, Levy, David N., Pasternak, Alexander O., O'Doherty, Una
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology 2016
Schlagworte:
Genome Replication and Regulation of Viral Gene Expression
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4810694/
https://ncbi.nlm.nih.gov/pubmed/26537682
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01913-15
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