Tumor Suppressor Interferon-Regulatory Factor 1 Counteracts the Germinal Center Reaction Driven by a Cancer-Associated Gammaherpesvirus

Gammaherpesviruses are ubiquitous pathogens that are associated with the development of B cell lymphomas. Gammaherpesviruses employ multiple mechanisms to transiently stimulate a broad, polyclonal germinal center reaction, an inherently mutagenic stage of B cell differentiation that is thought to be...

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Detalhes bibliográficos
Publicado no:J Virol
Main Authors: Mboko, Wadzanai P., Olteanu, Horatiu, Ray, Avijit, Xin, Gang, Darrah, Eric J., Kumar, Suresh N., Kulinski, Joseph M., Cui, Weiguo, Dittel, Bonnie N., Gauld, Stephen B., Tarakanova, Vera L.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2016
Assuntos:
Pathogenesis and Immunity
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4810652/
https://ncbi.nlm.nih.gov/pubmed/26719266
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.02774-15
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