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Involvement of the N-Terminal Deubiquitinating Protease Domain of Human Cytomegalovirus UL48 Tegument Protein in Autoubiquitination, Virion Stability, and Virus Entry

Human cytomegalovirus (HCMV) protein pUL48 is closely associated with the capsid and has a deubiquitinating protease (DUB) activity in its N-terminal region. Although this DUB activity moderately increases virus replication in cultured fibroblast cells, the requirements of the N-terminal region of p...

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Bibliographische Detailangaben
Veröffentlicht in:J Virol
Hauptverfasser: Kim, Young-Eui, Oh, Se Eun, Kwon, Ki Mun, Lee, Chan Hee, Ahn, Jin-Hyun
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology 2016
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4810636/
https://ncbi.nlm.nih.gov/pubmed/26764006
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.02766-15
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