Primary B Lymphocytes Infected with Kaposi's Sarcoma-Associated Herpesvirus Can Be Expanded In Vitro and Are Recognized by LANA-Specific CD4(+) T Cells

Kaposi's sarcoma-associated herpesvirus (KSHV) has tropism for B lymphocytes, in which it establishes latency, and can also cause lymphoproliferative disorders of these cells manifesting as primary effusion lymphoma (PEL) and multicentric Castleman disease (MCD). T cell immunity is vital for th...

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Bibliographic Details
Published in:J Virol
Main Authors: Nicol, Samantha M., Sabbah, Shereen, Brulois, Kevin F., Jung, Jae U., Bell, Andrew I., Hislop, Andrew D.
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 2016
Subjects:
Pathogenesis and Immunity
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4810529/
https://ncbi.nlm.nih.gov/pubmed/26819313
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.02377-15
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