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A GIPC1-Palmitate Switch Modulates Dopamine Drd3 Receptor Trafficking and Signaling

Palmitoylation is involved in several neuropsychiatric and movement disorders for which a dysfunctional signaling of the dopamine D3 receptor (Drd3) is hypothesized. Computational modeling of Drd3's homologue, Drd2, has shed some light on the putative role of palmitoylation as a reversible swit...

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Publicado en:Mol Cell Biol
Autores principales: Arango-Lievano, Margarita, Sensoy, Ozge, Borie, Amélie, Corbani, Maithé, Guillon, Gilles, Sokoloff, Pierre, Weinstein, Harel, Jeanneteau, Freddy
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Microbiology 2016
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4810479/
https://ncbi.nlm.nih.gov/pubmed/26787837
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.00916-15
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