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Utp14 Recruits and Activates the RNA Helicase Dhr1 To Undock U3 snoRNA from the Preribosome

In eukaryotic ribosome biogenesis, U3 snoRNA base pairs with the pre-rRNA to promote its processing. However, U3 must be removed to allow folding of the central pseudoknot, a key feature of the small subunit. Previously, we showed that the DEAH/RHA RNA helicase Dhr1 dislodges U3 from the pre-rRNA. D...

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Pubblicato in:Mol Cell Biol
Autori principali: Zhu, Jieyi, Liu, Xin, Anjos, Margarida, Correll, Carl C., Johnson, Arlen W.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Microbiology 2016
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4810474/
https://ncbi.nlm.nih.gov/pubmed/26729466
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.00773-15
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