Dissecting Stages of Human Kidney Development and Tumorigenesis with Surface Markers Affords Simple Prospective Purification of Nephron Stem Cells

When assembling a nephron during development a multipotent stem cell pool becomes restricted as differentiation ensues. A faulty differentiation arrest in this process leads to transformation and initiation of a Wilms’ tumor. Mapping these transitions with respective surface markers affords accessib...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Pode-Shakked, Naomi, Pleniceanu, Oren, Gershon, Rotem, Shukrun, Rachel, Kanter, Itamar, Bucris, Efrat, Pode-Shakked, Ben, Tam, Gal, Tam, Hadar, Caspi, Revital, Pri-Chen, Sara, Vax, Einav, Katz, Guy, Omer, Dorit, Harari-Steinberg, Orit, Kalisky, Tomer, Dekel, Benjamin
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2016
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4810363/
https://ncbi.nlm.nih.gov/pubmed/27020553
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep23562
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