The Iminosugar UV-4 is a Broad Inhibitor of Influenza A and B Viruses ex Vivo and in Mice

Iminosugars that are competitive inhibitors of endoplasmic reticulum (ER) α-glucosidases have been demonstrated to have antiviral activity against a diverse set of viruses. A novel iminosugar, UV-4B, has recently been shown to provide protection against lethal infections with dengue and influenza A...

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Detalhes bibliográficos
Publicado no:Viruses
Main Authors: Warfield, Kelly L., Barnard, Dale L., Enterlein, Sven G., Smee, Donald F., Khaliq, Mansoora, Sampath, Aruna, Callahan, Michael V., Ramstedt, Urban, Day, Craig W.
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2016
Assuntos:
Communication
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4810261/
https://ncbi.nlm.nih.gov/pubmed/27072420
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/v8030071
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